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TruReleaf MD Jackson Medical Marijuana Clinic As of 2020 Jackson Mississippi boasts a population of 153701 according to the 2020 census. Jackson was founded in 1821 and is named after General Andrew Jackson. Mississippi has a rich history and the state is home to just under three million people. Jackson is the capital of Mississippi and the most populated city. As a result thousands of individuals have begun finding relief through the use of medical marijuana. Our medical marijuana doctor in Jackson Mississippi is experienced in treating a number of qualifying conditions. Medical marijuana became legal in Mississippi in February 2022.